CELLCOMM INFRASTRUCTURE

10x Xenium Station

A precise molecular understanding of the heterogeneity of tissues in higher organisms is crucial for answering a range of key biomedical questions. The 10x Xenium Station enables detailed molecular analysis of defined regions within complex, heterogeneous tissue samples at both the protein and mRNA levels in high-plex formats. The technology provides a spatial-molecular image of complex biological samples by generating whole-transcriptome data and profiling data for hundreds of validated protein analytes from selected tissue sections. This enables researchers to investigate the manifold cellular and molecular interactions – for example, between cancer cells, cells of the microenvironment and therapeutically relevant immune system cells – with unprecedented precision. The 10x Xenium Station thus represents a robust and flexible technology platform that significantly accelerates the journey from the discovery of biomedically relevant processes to translational research questions.

For further information please contact CF Genomics

Orbitrap Ascend BioPharma Tribrid MS

The Orbitrap Ascend BioPharma Tribrid System is a mass spectrometer used for the analysis of small molecules as well as the characterization of biotherapeutics such as monoclonal antibodies (mAbs). It is equipped with a quadrupole mass filter, a linear ion trap, and a high-field Orbitrap mass analyzer, as well as multiple fragmentation techniques (CID, HCD, ETD/EThcD, and UVPD).

For further information please contact CF Bioanalytik

CytoFLEX S Mosaic 63

CytoFLEX S Mosaic 63 is a benchtop high-parameter spectral flowcytometer with 4 lasers (405 nm, 488 nm, 561 nm and 638 nm) and a total of 63 detection channels.
The device enables the analysis of cells through specific labelling with fluorescent antibodies. Unlike the conventional flowcytometry, this device can do a full spectral analysis, improving the overall quality and number of detection channels significantly higher. This is next generation technology of flowcytometry and will becoming the method of choice, particularly in the field of immunology. It enables in-depth investigation and characterization of individual cells and populations.

For further information please contact CF Flow cytometry

GPU Node

SCC ( Salzburg Collaborative Computing) provides high-performance computing resources to researchers in Salzburg. Within this cluster, Cellcom runs a GPU node equipped with two NVIDIA H100 NVL GPUs with 96GB VRAM each, two AMD EPYC 9334 CPUs with 32 cores each, 2.3 TB DDR5 RAM, and HDR100 Infiniband. This node facilitates analyses of single-cell spatial datasets and training of neural network-based algorithms.

For further information please contact CF Bioinformatics