The Centre for the Study of the Christian East (ZECO) of Paris Lodron University of Salzburg in cooperation with the International Institute for Central Asian Studies (IICAS) of the UNESCO Silk Road Programme, held a high-profile academic conference in Samarkand, Uzbekistan in September 2023. In a unique interdisciplinary synopsis of theology, religious studies and history, archaeology, philology, manuscript studies and epigraphy, the latest research on the “Church of the East” was exchanged.