2021

Paper Publications

Peer-reviewed

Hinterholzer A., Stanojlovic V., Regl C., Huber C. G., Cabrele C., Schubert M.
Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy
J. Biomol. NMR 75, 71–82 (2021)

Lebede M., Di Marco F., Esser-Skala W., Hennig R., Wohlschlager T., Huber C. G.
 Exploring the Chemical Space of Protein Glycosylation in Noncovalent Protein Complexes: An Expedition Along Different Structural Levels of Human Chorionic Gonadotropin Employing Mass Spectrometry
Anal. Chem. 93(30), 10424–10434 (2021)

Di Marco F., Berger T., Esser-Skala W., Rapp E., Regl C., Huber C. G.
Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-based Biotherapeutics
Int. J. Mol. Sci. 22, 9072 (2021)

Böttinger K., Esser-Skala W., Paul K., Herwig C., Huber C. G.
 At-line quantitative profiling of monoclonal antibody products during bioprocessing using HPLC-MS
Anal. Chim. Acta. 1207, 339813 (2022)

Kohlberger M., Gadermaier G.
SELEX: Critical factors and optimization strategies for successful aptamer selection
Biotechnol. Appl. Biochem. 69(5), 1771–1792 (2022)

Participation in Conferences

Talks

Di Marco F.
Glycoform assessment of the non-covalent human chorionic gonadotropin dimer using hybrid mass spectrometry and multi-level data integration
31. Doktorandenseminar des Arbeitskreises Separation Science in der Fachgruppe Analytische Chemie der Gesellschaft Deutscher Chemiker, Hohenroda (Germany), 11.–12.01.2021

Huber C.G.
Exploring the chemical space of modifications in therapeutic proteins employing chromatography, mass spectrometry, and bioinformatics
First Agilent Virtual InfinityLab LC 2021 Conference, online, 22.–23.06.2021

Böttinger K.
Quantification of minor abundant glycosylation variants of mAbs
16th ASAC JunganalytikerInnen Forum, online, 11.–12.06.2021

Huber C.G.
Title Quality Attributes of Therapeutic Proteins Determined by Chromatography and/or Mass Spectrometry: Who Senses the Difference?
Thermo Innovation Summit, online, 13.–17.09.2021

Organisation of Scientific Events

38th Winterschool on Proteinases and Inhibitors
online, 24.–26.02.2021

16th ASAC Junganalytikerforum
online, 11.–12.06.2021

National and International Cooperations

C. Herwig
CD-Laboratory for Mechanistic and Physiological Methods for more Efficient Bioprocesses, Technical University Vienna, Austria

N. Kelleher
Northwestern University, Chicago, IL (USA)

S. Cianferani
Université de Strasbourg, Strasbourg (France)

O. Kohlbacher
Applied Bioinformatics Group, University of Tübingen, Tübingen (Germany)

S. Koen
Research Institute for Chromatography, Katrijk (Belgium)

E. Rapp
GlyXera, Magdeburg (Germany)

A. Alpert
PolyLc. Inc., Columbia (Belgium)