Recent Publications

Recent Publications
Team (from left to right): Dr. Lorenz Aglas, Litty Johnson and Mario Wenger

Recent Publication in JoVE

Our publication, entitled "Humanized Mediator Release Assay as a Read-Out for Allergen Potency" (doi: 10.3791/627029, was published on June 29, 2021 in the section "Immunology and Infection". Authors: Mario Wenger, Athanasios Bethanis, Litty Johnson, and Lorenz Aglas.

12 Most Important Academic Publications


Handb Exp Pharmacol.

Pointner LN, Ferreira F, Aglas L. B Cell Functions in the Development of Type I Allergy and Induction of Immune Tolerance. Handb Exp Pharmacol. 2021 Jul 2. doi: 10.1007/164_2021_479. Epub ahead of print. PMID: 34196808.


J Vis Exp. (JoVE)

Wenger M, Bethanis A, Johnson L, Aglas L. Humanized Mediator Release Assay as a Read-Out for Allergen Potency. J Vis Exp. 2021 Jun 29;(172). doi: 10.3791/62702. PMID: 34279512.


J Allergy Clin Immunol.

Wolf M, Aglas L, Twaroch TE, Steiner M, Huber S, Hauser M, Hofer H, Parigiani MA, Ebner C, Bohle B, Briza P, Neubauer A, Stolz F, Wallner M, Ferreira F. Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity. J Allergy Clin Immunol. 2018 Apr;141(4):1488-1491.e5. doi:

12 Most Important Academic Publications


Frontiers in Immunology

Aglas L, Bethanis A, Chrusciel P, Stolz F, Gruen M, Jaakkola UM, Jongejan L, Yatkin E, Van Ree R. In vivo Induction of Functional Inhibitory IgG Antibodies by a Hypoallergenic Bet v 1 Variant. Front Immunol. 2020 Sep 3;11:2118. doi: 10.3389/fimmu.2020.02118. PMID: 33013894; PMCID: PMC7494741.


Clin. Transl. Allergy

Pointner L, Bethanis A, Thaler M, Traidl-Hoffmann C, Gilles S, Ferreira F, Aglas L. Initiating pollen sensitization – complex source, complex mechanisms. Clin Transl Allergy. 2020 Aug 31;10:36. doi: 10.1186/s13601-020-00341-y. PMID: 32884636; PMCID: PMC7461309.


Curr Allergy Asthma Rep.

Aglas L, Soh WT, Kraiem A, Wenger M, Brandstetter H, Ferreira F.; Ligand Binding of PR-10 Proteins with a Particular Focus on the Bet v 1 Allergen Family. Curr Allergy Asthma Rep. 2020 May 19;20(7):25. doi: 10.1007/s11882-020-00918-4. PMID: 32430735.

12 Most Important Academic Publications



da Silva ES, Aglas L, Pinheiro CS, de Andrade Belitardo EMM, Silveira EF, Huber S, Torres RT, Wallner M, Briza P, Lackner P, Laimer J, Pacheco LGC, Cruz ÁA, Alcântara-Neves NM, Ferreira F. A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate. Clin Exp Allergy. 2020 Ap


J Allergy Clin Immunol.

Gökkaya M, Damialis A, Nussbaumer T, Beck I, Bounas-Pyrros N, Bezold S, Amisi MM, Kolek F, Todorova A, Chaker A, Aglas L, Ferreira F, Redegeld FA, Brunner JO, Neumann AU, Traidl-Hoffmann C, Gilles S. Defining biomarkers to predict symptoms in subjects with and without allergy under natural pollen exposure. J Allergy Clin Immunol. 2020 Apr 6:S0091-6749(20)30419-X. doi: 10.1016/j.jaci.2020.02.037. Epub ahead of print. PMID: 32272131.



Araujo GR, Aglas L, Vaz ER, Machado Y, Huber S, Himly M, Duschl A, Goulart LR, Ferreira F. TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice. Allergy. 2020 Apr;75(4):882-891. doi: 10.1111/all.14108. Epub 2019 Dec 12. PMID: 31750952; PMCID: PMC7217028.

12 Most Important Academic Publications



Soh WT, Aglas L*, Mueller GA, Gilles S, Weiss R… Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity. Allergy. 2019 Dec;74(12):2382-2393. doi: 10.1111/all.13948. Epub 2019 Oct 8. PMID: 31230350; PMCID: PMC6910946. *shared first authorship


J Allergy Clin Immunol.

Aglas L, Gilles S, Bauer R, Huber S, Araujo GR, Mueller G, Scheiblhofer S, Amisi M, Dang HH, Briza P, Bohle B, Horejs-Hoeck J, Traidl-Hoffmann C, Ferreira F. Context matters: T<sub>H</sub>2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity. J Allergy Clin Immunol. 2018 Sep;142(3):984-987.e6. doi: 10.1016/j.jaci.2018.05.004. Epub 2018 May 18. PMID: 29782896; PMCID: PMC6129402.


Front Physiol.

Müller E, Pröller P, Ferreira-Briza F, Aglas L, Stöggl T. Effectiveness of Grounded Sleeping on Recovery After Intensive Eccentric Muscle Loading. Front Physiol. 2019 Jan 28;10:35. doi: 10.3389/fphys.2019.00035. PMID: 30745882; PMCID: PMC6360250.


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