Publications, Talks, and Presentations





Präsentations at national and international meetings

More than 35 invited talks, >140 oral and poster presentations at highly recognized meetings, including NanoSafety Cluster NanoWeeks and NanoSafe Congress, International NanoToxicology Congress, 15th International Conference on Nanomedicine in China, Eurotox, World Immune Regulation Meetings (WIRM), Meetings of the Collegium Internationale Allergologicum (CIA), the European Academy of Allergy and Clinical Immunology (EAACI), American Association of Asthma, Allergy, and Immunology (AAAAI), the European Congress of Immunology (ECI), etc.

Scientific committee and organizer of international conferences

  • 15th OeGMBT Annual Meeting – Life Sciences and cutting edge technologies, Salzburg, Austria – September 2023
  • nanoSAFE & NanoSafety Cluster Joint Conference 2023 Grenoble, France – June 2023
  • Nano Training School 2023, Venice, Italy – May 2023
  • NanoWeek 2022, Limassol, Cyprus – June 2022
  • Nano Training School 2022, Venice, Italy – May 2022
  • NanoSAFE Digital Conference 2021 – November 2020
  • 12th International Particle Toxicology Conference, Salzburg, Austria – Septmeber 2019
  • 1st International Young Scientsts Forum, Salzburg, Austria – September 2019
  • 1st Open NanoScience Congress, Salzburg, Austria – February 2019

Peer-reviewed publications


Zhang G., Wang X., Wang G., Suo X., Qiu Y., Luo R.-H., Liu Y., Li Q., Shi Z., Liu F., Li Z., Qu J., Bastus N.g., Himly M., Wang L., Liu F.-L., Zheng Y.-T., Puntes V., and Li Y.
Nanoparticles insert a three dimensional cavity structure of proteins for function inhibition: The Case of CeO2 and SARS-CoV-2 (2024).
Nano Today 55:102183. DOI:



Maier D., Exner T., Papadiamantis A.G., Ammar A., Tsoumanis A., Doganis P., Rouse I., Slater L.T., Gkoutos G., Jeliazkova N., Ilgenfritz H., Ziegler M., Gerhard B., Kopetsky S., Joshi D., Walker L., Svendsen C., Sarimveis H., Lobaskin V., Himly M., van Rijn J., Winckers L., Acosta J.M., Willighagen R., Melagraki G., Lynch I., and Afantitis A.
Harmonising knowledge for safer materials via the “NanoCommons” Knowledge Base (2023).
Front. Phys. Soft Matter Phys. 11:1271542. DOI:
Accepted without changes!


Casonato Melo C., Fux A.C., Himly M., Bastus N.L., Schlahsa L., Siewert C., Puntes V., Duschl A., Gessner I., and Feuerbach J.A.Recovering what matters: high protein recovery after endotoxin removal with anti-Lipid A antibody microparticle conjugates from LPS-contaminated complex protein samples (2023).
Int. J. Mol. Sci. 24(18), 13971. DOI:
PLUS-Paper of the Month November 2023


Graphical abstractDumit V., Ammar A., Bakker M., Banares M., Bossa C., Costa A., Cowie H., Drobne D., Exner T., Farcal L., Friedrichs S., Furxhi I., Haase A., Himly M., Jeliazkova N., Lynch I., Maier D., Noorlander C.W., Soler-Illia G., Suarez-Merino B., Willighagen E., and Nymark P.
From principles to reality: FAIR implementation in the nanosafety community (2023).
Nano Today 51:101923. DOI:


STEM image of ZnO NPs

Wolfgruber S., Rieger J., Cardozo O., Punz B., Himly M., Stingl A., Farias P.M.A., Abuja P.M., and Zatloukal K.
Antiviral activity of zinc oxide nanoparticles against SARS-CoV-2 (2023)
Intern. J. Mol. Sci. 24(9):8425. DOI:


graphical abstract

Fux A.C., Casonato Melo C., Michelini S., Swartzwelter B.J., Neusch A., Italiani P., and Himly M.
Heterogeneity of lipopolysaccharide as source of variability in bioassays and LPS binding proteins as remedy (2023).
Intern. J. Mol. Sci. 24(9):8395. DOI:


graphical abstractJohnson L., Aglas L., Punz B., Dang H., Christ C., Pointner L., Wenger M., Hofstätter N., Hofer S., Geppert M., Andosch A., Ferreira F., Horejs-Hoeck J., Duschl A., and Himly M.
Mechanistic insights into silica nanoparticle-allergen interaction on antigen presenting cell function in the context of allergic reactions (2022).
NanoScale 15:2262-75. DOI:
PLUS-Paper of the Month March 2023


graphical abstractSchürz M., Danmayr J., Jritsch M., Klinglmayr E., Melo-Benirschke H., Matea C.-T., Zimmerebner P., Rauter J., Wolf M., Gomes F.G., Kratochvil Z., Heger Z., Miller A., Heuser T., Stanojlovic V., Kiefer J., Plank T., Johnson L., Himly M., Blöchl C., Huber C.G., Hintersteiner M., and Meisner-Kober N.
EVAnalyzer: High content imaging for rigorous characterisation of single extracellular vesicles using standard laboratory equipment and a new open-source ImageJ/Fiji plugin (2022).
J Extracell. Ves. 12:12282. DOI:
PLUS-Paper of the Month November 2022


Graphical abstract

Hasenkopf I., Mills-Goodlet R., Johnson L., Rouse I., Geppert M,. Duschl A., Maier D., Lobaskin V., Lynch I., and Himly M.
Computational prediction and experimental analysis of the nanoparticle-protein corona: showcasing an in vitro-in silico workflow providing FAIR data (2022).
Nano Today 46:101561. DOI:
PLUS-Paper of the Month December 2022


Mullins M., Himly M., Rodriguez Llopis I., Furxhi I., Hofer S., Hofstätter N., Wick P., Romeo D., Kuehnel D., Siivola K., Catalan J., Hund-Rinke K., Xiarchos I., Linehan S., Schuurbiers D., García Bilbao A., Barruetabena L., and Drobne D.(Re)Conceptualizing decision making tools in a risk governance framework for emerging technologies – the case of nanomaterials (2022).Environment Systems and Decisions. DOI:


Graphical abstractPunz B., Johnson L., Geppert M., Dang H.-H., Horejs-Hoeck J., Duschl A., and Himly M.
Surface functionalization of silica nanoparticles: strategies to optimize the immune-activating profile of biopharmaceutical carrier platforms (2022).
Pharmaceutics 14:1103. DOI:
PLUS-Paper of the Month July 2022


Figure 4Lima T.S.M., de Souza W., Geaquinto L.R.O., Sanches P.L., Stepień E.L., Meneses J., Fernández de Gortari E., Meisner-Kober N., Himly M., Granjeiro J.M., and Ribeiro A.R.L.P.
Nanomaterials exposure, extracellular vesicles biogenesis and adverse cellular outcomes: a scoping review (2022).
Nanomaterials 12:1231. DOI:


Graphical abstractHofer S., Hofstätter N., Punz B., Hasenkopf I., Johnson L., and Himly M.
Immunotoxicity of nanomaterials in health and disease: current challenges and emerging approaches for identifying immune modifiers in susceptible populations (2022).
WIREs Nanomed. Nanobiotechnol. 14:e1804. DOI:




Nanotopography impacts 3D fold

Mills-Goodlet R., Johnson L., Hoppe I.J., Regl C., Geppert M., Schenck M., Huber S., Hauser M., Ferreira F., Hüsing N.,, Huber C.G., Brandstetter H., Duschl A., and Himly M.
The nanotopography of SiO2 particles impacts selectivity and 3D fold of bound allergens (2021).
Nanoscale 13:20508-20. DOI:
PLUS-Paper of the Month May 2022


Graphical abstract

Hofstätter N., Hofer S., Duschl A., and Himly M.
Children’s privilege in COVID-19: The protective role of the juvenile lung morphometry and ventilatory pattern on airborne SARS-CoV-2 transmission and severe pulmonary disease (2021).
Biomedicines 9(10):1414. DOI:
PLUS news item from Dec 2, 2021
PLUS-Paper of the Month February 2022


Early decision making in vaccine development

Johnson L., Aglas L., Soh W.T., Geppert M., Hofer S., Hofstätter N., Briza P., Ferreira F., Weiss R., Brandstetter H., Duschl A., and Himly M.
Structural alterations of antigens at the material interface: an early decision toolbox facilitating Safe-by-Design nanovaccine development (2021).
Int. J. Mol. Sci. 22(19):10895. DOI:
PLUS-Paper of the Month December 2021


Geppert M. and Himly M.
Iron oxide nanoparticles in bioimaging – an immune perspective (2021).
Front. Immunol. 12:688927. DOI:


Aerosols determine prognosisHofer S., Hofstätter N., Duschl A., and Himly M.
SARS-CoV-2-laden respiratory aerosol deposition in the lung alveolar-interstitial region is a potential risk factor for severe disease: a modeling study (2021).
J. Personalized Med. 11(5):431. DOI:
WHO-listed research article ID
:  covidwho-1234764
PLUS-Paper of the Month July 2021
PLUS news item from July 8, 2021


EC4SN in Risk Governance landscapeMarcoulaki, E. Lopez de Ipiña, J.M., Vercauteren, S., Bouillard, J., Himly, M., Lynch, I., Witters, H., Shandilya, N., van Duuren-Stuurman, B., Kunz, V., Unger, W.E.S., Hodoroaba, V.-D., Bard, D., Evans, G., Alstrup Jensen, K., Pilou, M., Viitanen, A.-K., Bochon, A., Duschl, A., Geppert, M., Persson, K., Cotgreave, I., Niga, P., Scalbi, S., Caillard, B., Arevalillo A., Frejafon E., Aguerre-Chariol O., and Dulio, V.
Blueprint for a self-sustained European Centre for service provision in safe and sustainable innovation in nanotechnology (2021).
NanoImpact 23:100337. DOI:


Environament impacting human healthSwartzwelter B.J., Fux A.C., Johnson L., Swart E., Hofer S., Hofstätter N., Geppert M., Italiani P., Boraschi D., Duschl A., and Himly M.
The impact of nanoparticles on innate immune activation by live bacteria.
Int. J. Mol. Sci. 21(24): 9695. DOI:


NInChI alphaLynch I., Afantitis A., Exner T., Himly M., Willighagen E., Lobaskin V., Doganis P., Liampa I., Harper S., Maier D., Papadiamantis A., Matzke M., Green Etxabe A., Rybinska-Fryca A., Gromelski M., Bossa N., Serra A., Sanabria N., Tämm K., Johnson B., Jensen A., Kohonen P., Slater L., Sarimveis H., Melagraki G. Can an InChI for nano address the need for a simplified representation of complex nanomaterials across experimental and nanoinformatics studies? (2020).
Nanomaterials. 10(12):2493. DOI:


Papadiamantis A.G., Klaessig F.C., Exner E.T., Hofer S., Hofstätter N., Himly M., Williams M.A., Doganis P., Hoover M.D., Afantitis A., Melagraki G., Nolan T.S., Rumble J., Maier D., Lynch I. and members of the NCI nanoWG.Metadata stewardship in nanosafety research: community-driven organisation of metadata schemas to support FAIR nanoscience data (2020).Nanomaterials 10(10):2033. DOI:

Submersed vs- ALI culture conditionsMills-Goodlet R., Schenck M., Chary A., Geppert M., Serchi T., Hofer S., Hofstätter N., Feinle A., Hüsing N., Gutleb A.C., Himly M., and Duschl A.
Biological effects of allergen-nanoparticle conjugates: uptake and immune effects determined on hAELVi cells under submerged vs. air-liquid interface conditions (2020).
Environ. Sci. Nano. 7:2073-2086. DOI:
PLUS-Paper of the Month November 2020


Particulates impacting human healthJoubert I.A., Geppert M., Johnson L., Mills-Goodlet R., Michelini S., Korotchenko E., Duschl A., Weiss R., Horejs-Hoeck J., and Himly M.
Mechanisms of particles in sensitization, effector function and therapy of allergic disease (2020).
Front Immunol. 11:1334. DOI:


Johnson L., Duschl A., and Himly M.
Nanotechnology-Based Vaccines for Allergen-Specific Immunotherapy: Potentials and Challenges of Conventional and Novel Adjuvants under Research (2020).
Vaccines 8(2), 237; DOI:

Reichenfelser R., Punz E., Joubert I.A., Geppert M., and Himly M.
Nano-bio interactions (2020).
Open Schools Journal for Open Science, 1. DOI:

Aydin H., Nestelbacher R., Joubert I.A., Geppert M., and Himly M.
Neat and clean – effects of nanosurfaces (2020)
Open Schools Journal for Open Science, 1. DOI:

Winkler L., Woess I., Joubert I.A., Geppert M., and Himly M.
Nanomedicine (2020).
Open Schools Journal for Open Science, 1. DOI:

Manaj L., Manaj L., Joubert I.A., Geppert M., and Himly M.
Nano-chip for cancer diagnostics (2020).
Open Schools Journal for Open Science, 1. DOI:

Nys L., Raeuschl P., Ess S., Nestelbacher R., Joubert I.A., Geppert M., and Himly M.
Drug targeting in cancer therapy (2020).
Open Schools Journal for Open Science, 1. DOI:

Kroath M., Punz E., Joubert I.A., Himly M., and Geppert M.
Toxicity of azo-dyes combined with TiO2 nanoparticles (2020).
Open Schools Journal for Open Science, 1. DOI:

Staudinger M., Punz E., Joubert I.A., Himly M., and Geppert M.
Nanotechnology in sweets (2020).
Open Schools Journal for Open Science, 1. DOI:

Parak N., Lippusch M., Naylor C., Steyskall A., Joubert I.A., Himly M., and Geppert M.
Gold and silver – but safe? (2020).
Open Schools Journal for Open Science, 1. DOI:

Manaj L., Johnson L., Punz E., Joubert I.A., Geppert M., and Himly M.
Medial applications based on nanotechnology (2020).
Open Schools Journal for Open Science, 1. DOI:

Collavo G., Lalayev A., Angerer S., Kraml M., Bachner S., Kirchgasser K., Schmeel J., Trummer C., Joubert I.A., Geppert M., Schaffer K., Nestelbacher R., and Himly M.
Nan-O-Style – experiments and arts (2020).
Open Schools Journal for Open Science, 1. DOI:

Kypriotis E., Ess S., Joubert I.A., Nestelbacher R., Geppert M., and Himly M.
Editorial for special issue articles from the 1st International NanoScience Congress (2020).
Open Schools Journal for Open Science, 1. DOI:

Erian J., Vince L.-M., Duerrauer V., Rainer L., Geppert M., Joubert I.A., and Himly M.
Active drug targeting (2020).
Open Schools Journal for Open Science, 1. DOI:

Peneder H., Punz E., Joubert I.A., Geppert M., and Himly M.
Nanoparticle tracking analysis (2020).
Open Schools Journal for Open Science, 1. DOI:


Epithelial barrier disruptionHimly M., Geppert M., Hofer S., Hofstaetter N., Horejs-Hoeck J., and Duschl A.
When would immunologists consider a nanomaterial to be safe: recommendations for planning studies on nanosafety (2020).
Small 16(21):1907483. DOI:


Study designGeppert M., Schwarz A., Stangassinger L.M., Wenger S., Wienerroither L.M., Ess S., Duschl A., and Himly M.
Interactions of TiO2 nanoparticles with ingredients from modern lifestyle products and their effects on human skin cells (2020).
Chem. Res. Toxicol. 33(5):1215-1225. DOI:




Study designJoubert I.A., Geppert M., Ess S., Nestelbacher R., Gadermaier G., Duschl A., Bathke A., and Himly M.Public perception and knowledge on nanotechnology: A study based on a citizen science approach (2019).NanoImpact 17, 100201. Epub 2019 Nov 29. DOI: of the Month February 2020


Araujo G.R., Aglas L., Vaz E.R., Machado Y., Huber S., Himly M., Duschl A., Goulart L.R., Ferreira F.TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice (2019).Allergy. Epub 2019 Sep 30. DOI: of the Month December 2019


Ess S., Lindner C., Wienerroithner L., Nestelbacher R., Geppert M., Duschl A., and Himy M.Nan-O-Style: Nanotechnology <-> Modern Lifestyle (2018).p21-24. In Heigl, F., Dörler, D., and Ernst, M. (eds.) Austrian Citizen Science Conference 2018. Lausanne, CH: FrontiersIn Available at: DOI:


Study designGrotz B., Geppert M., Mills-Goodlet R., Hofer S., Hofstätter N., Asam C., Feinle A., Kocsis K., Berger T., Diwald O., Hüsing N., Wallner M., Ferreira F., Duschl A., and Himly M.Biologic effects of nanoparticle-allergen conjugates: Time-resolved uptake using an in vitro lung epithelial co-culture model of A549 and THP-1 cells (2018).Environ. Sci. Nano 5(9):2184-2197. DOI: of the Month September 2018


Frijns E., Verstraelen S., Stoehr L., van Laer J., Jacobs A., Boyles M.S.P., Geppert P., Madl P., Nelissen I., Duschl A., and Himly M.
A novel exposure system termed NAVETTA for in vitro laminar flow electrodeposition of nanoaerosol and evaluation of immune effects in human lung reporter cells (2017).
Environ Sci & Technol 51:5259-69. Epub 2017 Mar 24. DOI:
ACS editor’s choice. Cover page.

Cover page

Li Y., Shi Z., Radauer-Preiml I., Andosch A., Casals E., Luetz-Meindl U., Cobaleda M., Lin Z., Jaberi-Douraki M., Italiani P., Horejs-Hoeck J., Himly M., Monteiro-Riviere N., Duschl A., Puntes V., and Boraschi D.
Bacterial Endotoxin (LPS) Binds to the Surface of Gold Nanoparticles, Interferes with Biocorona Formation and Induces Human Monocyte Inflammatory Activation (2017).
Nanotoxicology 11(9-10):1157-1175. Epub 2017 Dec 1. DOI:

Stemeseder T., Klinglmayr E., Moser S., Lang R., Himly M., Oostingh G.J., Zumbach J., Bathke A.C., Hawranek T., and Gadermaier G.
Influence of intrinsic aspects and lifestyle factors on specific IgE sensitization in a non-selected, adolescent Austrian cohort (2017).
Intern Arch Allergy Immunol 173(2):99-104. Epub 2017 Jun 28. DOI:
PLUS-Paper of the Month June 2017

Figure 1Himly M., Mills-Goodlet R., Geppert M., and Duschl A.
Nanomaterials in the context of type II immune reactions – fears and potentials (2017).
Frontiers Immunol. 8:471. DOI:


Marquez A., Berger T., Feinle A., Hüsing N., Himly M., Duschl A., and Diwald O.
Enzyme Adsorption-induced Activity Changes:  A Quantitative Study on TiO2 Model Agglomerates (2017).
J. Nanobiotechnol. 15(1):55. Epub 2017 Jul 21. DOI:

Stemeseder T., Schweidler B., Doppler P., Klinglmayr E., Moser S., Lueftenegger L., Himly M., Lang R., Zumbach J., Oostingh G.J., Hawranek T., Bathke A.C., and Gadermaier G.
Exposure to indoor allergens in different residential settings and its influence on IgE sensitization in a geographically confined Austrian cohort (2017).
PloS One 12(1):e0168686. Epub 2017 Jan 3.  DOI:

Marquez A., Berger T., Feinle A., Hüsing N., Himly M., Duschl A., and Diwald O.
Bovine serum albumin adsorption on TiO2 colloids: the effect of particle agglomeration and surface composition (2017).
Langmuir 14(33):2551-8. Epub 2017 Feb 14. DOI:

Sancho A., Wallner M., Hauser M., Nagl B., Himly M., Asam C., Ebner C., Jahn-Schmid B., Bohle B., and Ferreira F.
T Cell Epitope-containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice (2017).
PLoS One 12(1):e0169784. Epub 2017 Jan 12. DOI:
PLUS-Paper of the Month February 2017

Stemeseder T., Klinglmayr E., Moser S., Lueftenegger L., Lang R., Himly M., Oostingh G.J., Zumbach J., Bathke A.C., Hawranek T., and Gadermaier G.
Cross-sectional study on allergic sensitization of Austrian adolescents using molecule-based IgE profiling (2016).
Allergy 72(5):754-63. Epub 2016 Oct 18. DOI:
PLUS-Paper of the Month October 2016

da Luz, C.M., Boyles M.S.P., Falagan-Lotsch P., Pereira M.R., Tutumi H.R., de Olivieira Santos E., Martins N.B., Himly M., Sommer A., Foissner I., Duschl A., Granjeiro J.M., and Leite P.E.C.
Poly-Lactic Acid Nanoparticles (PLA-NP) promote physiological modifications in lung epithelial cells and are internalized by clathrin-coated pits and lipid rafts (2017).
J. Nanobiotechnol. 15(1):11. Epub 2017 Jan 31. DOI:

Piret J.P., Bondarenko O., Boyles M.S.P., Himly M., Ribeiro A.R., Benetti F., Small C., Lima B., Potthoff A., Simion M., Dumortier E., Leite P.E.C., Balottin L., Granjeiro J.M., Ivask A., Kahru A., Radauer-Preiml I., Tischler U., Duschl A., Saout C., Anguissola S., Haase A., Jacobs A., Nelissen I., Misra S., and Toussaint O.Pan-European inter-laboratory studies on a panel of in vitro cytotoxicity and pro-inflammation assays for nanoparticles (2017).Arch. Toxicol. 91(6):2315-30. Epub 2016 Dec 10. DOI:

Hofer H., Hauser M., Asam C., Nagl B., Himly M., Briza P., Ebner C., Lang R., Hawranek T., Bohle B., Lackner P., Ferreira F., and Wallner M.
Tackling Bet v 1- and associated food allergies with a single hybrid protein (2017).
J Allergy Clin Immunol. 140(2):525-533. Epub 2016 Dec 6. DOI:
PLUS-Paper of the Month December 2016


Steiner M., Huber S., Harrer A., and Himly M.
The evolution of human basophil biology from neglect towards understanding of their immune functions (2016).
Biomed. Res. Intern. ID 8232830. DOI:

Himly M., Grotz B., Sageder M., Geppert M., and Duschl A.
Immune frailty and nanomaterials: The case of allergies (2016).
Current Bionanotechnol. 2. DOI:

Steiner M., Harrer A., and Himly M.
Basophil reactivity as biomarker in immediate drug hypersensitivity reactions – potential and limitations (2016).
Frontiers Pharmacol. 7:171. DOI:

Malsch I., Duschl A., Rutkowska-Zbik D., Himly M., Zadrozny T., Kiparissides C., Kammona O., Talesnik M., Rothschild Y., Rosenberg D., Szafran B., Queipo Rodriguez P., Lynch I., et al.
Current trends in nanoeducation for industry and society (2016).
Current Bionanotechnol. 2. DOI:

Steiner M., Hawranek T., Schneider M., Ferreira F., Horejs-Hoeck J., Harrer A., and Himly M.
Elevated Toll-like receptor-induced CXCL8 secretion in human blood basophils from allergic donors is independent of Toll-like receptor expression levels (2016).
PLoS One 11(2):e0149275. Epub 2016 Feb 12.
PLUS-Paper of the Month May 2016

Malsch I., Rutkowsk-Zbik D., Duschl A., Himly M., Zadrozny T., Kiparissides C., Kammona O., Talesnik M., Rothschild Y., Szafran B., et al.
Nanotechnology educational gaps for industry and society. In: Martin Mullins, Finbarr Murphy, Eamonn McAlea, eds.
Nanotechnology: Risk Assurance and Risk Transfer (book chapter in press). Springer Series on Innovation, Technology, and Knowledge Management.

Preiml I., Andosch A., Hawranek T., Luetz-Meindl U., Wiederstein M., Horejs-Hoeck J., Himly M., Boyles M.S.P., and Duschl A.
Nanoparticle-allergen interactions mediate human allergic responses: protein corona characterization and cellular responses (2016).
Part. Fibre Toxicol. 13(1):3. Epub 2016 Jan 16.
PLUS-Paper of the Month Apr 2016

Himly M., Nandy A., Kahlert H., Thilker M., Steiner M., Briza P., Neubauer A., Klysner S., van Ree R., Buchheit K.H., Vieths S., and Ferreira F.
Standardization of allergen products: 2. Detailed characterization of GMP-produced recombinant Phl p 5.0109 as European Pharmacopoeia reference standard (2016).
Allergy 71(4):495-504. Epub 2015 Dec 20.

Woodfolk, J.A., Glesner J., Wright P.W., Kepley C.L., Li M., Himly M., Muehling L.M., Gustchina A., Wlodawer A., Chapman M., and Pomes A.
Antigenic determinants of the bilobal cockroach allergen Bla g 2 (2016).
J Biol Chem. 291(5):2288-301. Epub 2015 Dec 7.


Boyles M.S.P., Kristl T., Andosch A., Zimmermann M., Tran N., Casals E., Himly M., Puntes V., Huber C., Luetz-Meindl U., and Duschl A.
Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components (2015).
J. Nanobiotechnol. 13(1):84. Epub 2015 Nov 18.
PLUS-Paper of the Month Dec 2015.

Izak-Nau E., Huk A., Reidy B., Uggerud H., Vadset M., Eiden S., Voetz M., Himly M., Duschl A., Dusinska M., and Lynch I.
Impact of storage time and conditions on silver nanoparticles’ physico-chemical properties and implications for their biological effects (2015).
RSC Advances 5: 84172. Epub 2015 Sep 25.

Stoehr L.C., Madl P., Boyles M.S.P., Zauner R., Wimmer M., Sommer A., Foissner I., Himly M., and Duschl A.
Electrostatic field-assisted deposition of diesel exhaust aerosol affects integrity of human lung cells (2015).
Environ. Sci. Technol. Acs.est.5b02503.
PLUS-Paper of the Month Jun 2015.

Stoehr L.C., Endes C., Radauer-Preiml I., Boyles M.S.P., Casals E., Balog S., Pesch M., Petri-Fink A., Rothen-Rutishauser B., Himly M., Clift M.J.D., and Duschl A.
Assessment of a panel of IL-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure under different cell culture conditions (2015).
Part. Fibre Toxicol. 12:29. Epub 2015 Sep 29.

Steiner M., Wedi B., Harrer A., Schneider M., Ferreira F., and Himly M.
Three further cases corroborate lack of specific IgE in selective severe provocation-confirmed diclofenac hypersensitivity. In: Galli S.J., Kim Y., eds.
Allergic diseases: from mechanisms to cures (2015). Pacini Editore, Pisa, Italy.

Schlinkert P., Casals E., Boyles M.S.P., Tischler U., Hornig E., Tran N., Zhao J., Himly M., Riediker M., Oostingh G.J., Puntes V., and Duschl A.
The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types (2015).
J. Nanobiotechnol. 13(1):1-18. Epub 2015 Jan 16.
PLUS-Paper of the Month Mar 2015.


Deressa T., Stoecklinger A., Wallner M., Himly M., Kofler S., Hainz K., Brandstetter J., Thalhamer J., and Hammerl P.
Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase (2014).
PLoS One 9(7): e102280. Epub 2014 Jul 15.

Boyles M.S.P., Stoehr L., Schlinkert P., Himly M., and Duschl A.
The significance and insignificance of carbon nanotube-induced inflammation (2014).
Fibers 2(1): 45-74. Epub 2014 Feb 19.

Deifl S, Kitzmüller C., Steinberger P., Himly M., Jahn-Schmid B., Fischer G.F., Zlabinger G., and Bohle B.
Differential activation of dendritic cells by toll-like receptors causes diverse differentiation of naive CD4+ T cells from allergic patients (2014).
Allergy 69(12):1602-9. Epub 2014 Aug 5.


Pichler U., Hauser M., Hofer H., Himly M., Hoflehner E., Steiner M., Mutschlechner S., Hufnagl K., Ebner C., Mari A., Briza P., Bohle B., Wiedermann-Schmidt U., Ferreira F., and Wallner M.
Allergen hybrids – next generation vaccines for Fagales pollen immunotherapy (2013).
Clin. Exp. Allergy 44(3): 438-49. Epub 2013 Dec 11.
PLUS-Paper of the Month Feb 2014.

Roulias A., Pichler U., Hauser M., Himly M., Hofer H., Lackner P., Ebner C., Briza P., Bohle B., Egger M., Wallner M., and Ferreira F.
Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis (2013).
Allergy 69(2): 208-15. Epub 2013 Nov 14.
PLUS-Paper of the Month Nov 2013.

Zaborsky N., Brunner M., Wallner M., Himly M., Karl T., Schwarzenbacher R., Ferreira F., and Achatz G.
Partial retraction: Antigen aggregation decides the fate of the allergic immune response. (2013).
J. Immunol. 190(8): 4432.

Vejvar E., Himly M., Briza P., Eichhorn S., Ebner C., Hemmer W., Ferreira F., and Gadermaier G.
Allergenic relevance of non-specific lipid transfer proteins 2: Identification and characterization of Api g 6 from celery tuber as a representative of a novel IgE-binding protein family (2013).
Mol. Nutr. Food Res. 57(11): 2061-70. Epub 2013 Aug 5.

Santos K.S., Gadermaier G., Vejvar E., Arcuri H.A., Galvao C.E., Yang A.C., Resende V.M., Martins C.O., Himly M., Mari A., Liso M., Scala E., Breiteneder H., Wagner S., Kalil J., Ferreira F., Castro F.M.
Novel allergens from ancient foods: Man e 5 from manioc (Manihot esculenta Cratz) cross-reacts with Hev b 5 from latex (2013).
Mol. Nutr. Food Res. 57(6): 1100-9. Epub 2013 Mar 25.

Himly M., Wallner M., Zaborsky N., Hauser M., Gadermaier G., Harrer A., and Ferreira F.
Physicochemical characterization of recombinant allergens and hypoallergenic variants (2013).
Arb Paul Ehrlich Inst Bundesinstitut Impfstoffe Biomed Arzneim Langen Hess. 97:101-5.


Himly M., Zaborsky N., Wallner M., Egger M., Schnidar H., Fiebig H., Neubauer A., Cromwell O., and Ferreira F.GMP-produced recombinant Phl p 5.0109: a model to investigate the influence of different formulations on allergen structure and uptake by dendritic cells. In: Marone G., Triggiani M., Genovese A., eds. Translational science: from basic to clinical immunology and allergy (2012). Pacini Editore, Pisa, Italy.

Weinberger E.E., Himly M., Myschik J., Hauser M., Altmann F., Isakovic A., Scheiblhofer S., Thalhamer J., and Weiss R.Generation of hypoallergenic neoglycoconjugates for dendritic cell-targeted vaccination: a novel tool for specific immunotherapy (2012).J. Control. Release 165(2): 101-9. Epub 2012 Nov 10.
PLUS-Paper of the Month Dec 2012.

Zaborsky N., Brunner M., Wallner M., Himly M., Karl T., Schwarzenbacher R., Ferreira F., and Achatz G.
Response to detection and analysis of unusual features in the structural model and structure factor data of a birch pollen allergen (2012).
Acta Crystallogr. Sect. F Biol. Cyrst. Commun. 68(4): 377.


Machado Y.J., Rabasa Y., Montesinos R., Cremata J., Besada V., Fuentes D., Castillo A., de la Luz K.R., Vazquez A.M., and Himly M.
Physicochemical and biological characterization of 1E10 anti-Idiotype vaccine (2011).
BMC Biotechnology 11:112.

Versteeg S.A., Bulder I. Himly M., van Capel T.M., van den Hout R., Koppelman S.J., de Jong E.S., Ferreira F., and van Ree R.
Glutaraldehyde-modified recombinant Fel d 1: a hypoallergen with negligible biological activity but retained immunogenicity (2011).
World Allergy Organ. J. 4(7):113-9.

Hauser M., Asam C., Himly M., Palazzo P., Voltoini S., Montanari C., Briza P., Bernardi M.L., Mari A., Ferreira F., and Wallner M.
Bet v 1-like pollen allergens of multiple Fagals species can sensitize atopic individuals (2011).
Clin. Exp. Allergy 41(12):1804-14.

Steiner M., Harrer A., Lang R., Schneider M., Ferreria F., Hawranek T., and Himly M.
Basophil activation test for investigation of IgE-mediated mechanisms in drug hypersensitivity (2011).
J. Vis. Exp. 55, pii: 3263. Epub 2011 Sep 16; doi: 10.3791/3263.

Glesner J., Wünschmann S., Li M., Gustchina A., Wlodawer A., Himly M., Chapman M.D., and Pomés A.
Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding (2011).
PLoS One 6(7): e22223. Epub 2011 Jul 15.

Wallner M., Hauser M., Himly M., Zaborsky N., Mutschlechner S., Harrer A., van Ree R., Briza P., Thalhamer J., Bohle B., Achatz G., and Ferreira F.
Reshaping the Bet v 1-fold modulates T-helper polarization (2011).
J. Allergy Clin. Immunol. 127(6): 1571-8.e9. Epub 2011 Mar 21.


Harrer A., Lang R., Grims R., Braitsch M., Hawranek T., Aberer W., Vogel L., Schmid W., Ferreira F., and Himly M.
Diclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolites (2010).
PLoS One 5(10):e13707. Epub 2010 Oct 28.

Leonard R., Wopfner N., Pabst M., Stadlmann J., Petersen B.O., Duus J.O., Himly M., Radauer C., Gadermaier G., Razzazi-Fazeli E., Ferreira F., and Altmann F.
A new allergen from ragweed (Ambrosia artemisiifolia) with homology to Art v 1 from mugwort (2010).
J. Biol. Chem. 285(35):27192-200.

Rispens T., Himly M., Ooievaar-De Heer P., den Bleker T., Aalberse R.C.
Traces of pFc’ in IVIG interact with human IgG Fc domains and counteract aggregation (2010).
Eur. J. Pharm. Sci. 40: 62-8. Epub 2010 Mar 6.

Gallego M., Iraola V., Himly M., Robinson D.S., Badiola C., Garcia-Robaina J.C., Briza P., Carnés J.
Depigmented-polymerized house dust mite allergoid: allergen content, induction of IgG4 and clinical response (2010).
Intern. Arch. Allergy Immunol. 153(1): 61-6.
Editor’s choice.

Gadermaier G., Jahn-Schmid B., Vogel L., Egger M., Himly M., Briza P., Ebner C., Bohle B., Vieths S., and Ferreira F.
Targeting post-translational modifications of Art v 1 for immunotherapy of Artemisia pollen allergy (2010).
Mol. Immunol. 47(6): 1292-8. Epub 2009 Dec 16.

Zaborsky N., Brunner M., Wallner M., Himly M., Karl T., Schwarzenbacher R., Ferreira F., and Achatz G.
Antigen aggregation decides the fate of the allergic immune response (2010).
J. Immunol. 184(2): 725-35. Epub 2009 Dec 7.

Harrer A., Egger M., Gadermaier G., Erler A., Hauser M., Ferreira F., and Himly M.
Characterization of plant food allergens: an overview on physicochemical and immunological techniques (2010).
Mol. Nutr. Food Res. 54(1): 93-112. Epub 2009 Dec 3.

Pokoj S., Lauer I., Fötisch K., Himly M., Mari A., Enrique E., San Miguel-Moncin M., Lidholm J., Vieths S., and Scheurer S.
Quality assessment of allergenic hazelnut LTP Cor a 8 produced in E. coli and P. pastoris (2010).
Prot. Expr. Purif. 69(1): 68-75. Epub 2009 Sep 3.


Himly M., Carnés J., Fernández-Caldas E., Briza P., and Ferreira F.
Characterization of allergoids (2009).
Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf. A. M. 96: 61-70.

Neske F., Schörner C., Buchheit K.H., Costanzo A., Hanschmann K.M., Himly M., Holzhauser T., Ferreira F., Kaul S., Vieths S., and van Ree R.
BSP090 – The follow-up to CREATE (2009).
Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf. A. M. 96: 12-20.

Wallner M., Himly M., Neubauer A., Erler A., Asam C., Ebner C., Briza P., and Ferreira F.
The influence of production quality on the immunologic behavior of birch pollen allergens (2009).
PLoS One 4(12): e8457. Epub 2009 Dec 24.

Gadermaier G., Harrer A., Girbl T., Palazzo P., Himly M., Briza P., Mari A., and Ferreira F.
Isoform identification and characterization of Art v 3, the lipid-transfer protein of mugwort pollen (2009).
Mol. Immunol. 46(10): 1919-24.

Harrer A., Erler A., Gadermaier G., Faltlhansl M., Ferreira F., and Himly M.
Methods for structural determination and epitope mapping of important food allergens. Chapter 3.4. In: Jedrychowski L. and Wichers H.J. (eds).
Chemical and biological properties of food allergens (2009). Taylor & Francis Group LLC, Boca Raton, FL, USA.

Himly M., Nony E., Chabre H., van Overvelt L., Neubauer A., van Ree R., Buchheit K.H., Vieths S., Moingeon P., and Ferreira F.
Standardization of allergen products: 1. Detailed characterization of cGMP-produced recombinant Bet v 1.0101 as biological reference preparation (2009).
Allergy. 64(7): 1038-45. Epub 2009 Jan 31.

Carnés J., Himly M., Gallego M.T., Iraola V., Robinson D., Fernández-Caldas E., and Briza P.
Detection of allergen composition and in vivo immunogenicity of depigmented allergoids of Betula alba (2009).
Clin. Exp. Allergy 39(3): 426-34.
First two authors contributed equally.
Editorial by Reuter A., Lüttkopf D., and Vieths S. New frontiers in allergen standardization (2009).Clin. Exp. Allergy 39(3): 307-9.

Egger M., Hauser M., Himly M., Wopfner N., Wallner M., and Ferreira F.
Development of recombinant allergens for diagnosis and therapy (2009).
Front. Biosci. E1: 77-90.


Chapman M.D., Ferreira F., Villalba M., Cromwell O.,  Bryan D., Becker W.M., Fernandez-Rivas M., Durham S., Vieths S., van Ree R., and the CREATE consortium (Himly M. within the consortium)
Executive Summary:  The European Union CREATE Project to Develop Purified Allergen Standards as Certified Reference Materials for Allergenic Products (2008).
J. Allergy Clin. Immunol. 122: 882-9.

Oberhuber C., Ma Y., Marsh J., Rigby N., Smole U., Radauer C., Alessandri S., Briza P, Zuidmeer L., Maderegger B., Himly M., Sancho A.I., van Ree R., Knulst A., Ebner C., Shewry P., Mills E.N.C, Wellner K., Breiteneder H., Hoffmann-Sommergruber K., and Bublin M.
Purification and characterisation of relevant natural and recombinant apple allergens (2008).
Mol. Nutr. Food Res. 52: S208-19.

Ma Y., Griesmeier U., Susani M., Radauer C., Briza P., Erler A., Bublin M., Alessandri S., Himly M., Vazquez-Cortes S., Rincon de Arellano I.R., Saxoni-Papageorgiou P., Knulst A.C., Fernandez-Rivas M., Hoffmann-Sommergruber K., and Breiteneder H.
Comparison of natural and recombinant forms of the major fish allergen parvalbumin from cod and carp (2008).
Mol. Nutr. Food Res. 52: S196-207.

Schmidt G., Gadermaier G., Pertl H., Siegert M., Oksman-Caldentey K.M., Ritala A., Himly M., Obermayer G., and Ferreira F.
Production of recombinant allergens in plants (2008).Phytochemistry Reviews 7: 539-52.

Bublin M., Lauer I., Oberhuber C., Alessandri S., Briza P., Radauer C., Himly M., Breiteneder H., Vieths S., and Hoffmann-Sommergruber K.
Production and characterization of an allergen panel for component-resolved diagnosis of celery allergy (2008).
Mol. Nutr. Food Res. 52: S241-50.

van Ree R. Chapman M.D., Ferreira F., Vieths S., Bryan D., Cromwell O., Villalba M., Durham S.D., Becker W.M., Himly M. et al.
The CREATE Project: development of certified reference materials for allergenic products and validation of methods for their quantification (2008).
Allergy 63: 310-26


Schneider P., Denk U., Breitenbach M., Richter K., Schmid-Grendelmeier P., Nobbe S., Himly M., Mari A., Ebner C., and Simon-Nobbe B.
Alternaria alternata NADP+-dependent mannitol dehydrogenase is an important fungal allergen (2006).
Clin. Exp. Allergy 36(12): 1513-24.

Ma Y., Zuidmeer L., Bohle B., Bolhaar S.T.H.,Gadermaier G.,Gonzalez-Mancebo E.,Fernandez-Rivas M., Knulst A.C., Himly M., Asero R.,Ebner C., van Ree R.,Ferreira F.,Breiteneder H., Hoffmann-Sommergruber K.
Characterisation of recombinant Mal d 4 and its application for component resolved diagnosis of apple allergy (2006).
Clin. Exp. Allergy 36(8): 1087-96.

Ferreira F., Wallner M., Gadermaier G., Erler A., Fritz G., Glatter O., Himly M., Briza P., van Ree R., and the CREATE Consortium.Physico-chemical characterization of candidate reference materials (2006).Arb. Paul Ehrlich Inst. Bundesamt Sera Impfstoffe Frankf. A. M. 95: 75-82.


Leonard R., Petersen B.O., Himly M., Kaar W., Wopfner N., Kolarich D., van Ree R., Ebner C., Duus J., Ferreira F., and Altmann F.
Two Novel Types of O-glycans on the Mugwort Pollen Allergen Art v 1 and their Role in Antibody Binding (2005)
J. Biol. Chem. 280(9): 7932-40.


Gadermaier G., Dedic A., Obermeyer G., Himly M., and Ferreira F.
Biology of Weed Pollen Allergens (2004).
Curr. Allergy Asthma Reports 4(5): 391-400.


Bauer R., Himly M., Dedic A., Ferreira F., Thalhamer J., and Hartl A.
Optimization of Codon Usage is Required for Effective Genetic Immunization Against Art v 1, the Major Allergen of Mugwort Pollen (2003).
Allergy 58: 1003-10.

Schmid-Grendelmeier P., Holzmann D., Himly M., Weichel M., Ferreira F., Tresch S., Rückert B., Menz G., Blaser K., Wüthrich B., and Crameri R.
Native and Recombinant Art v 1 are Able to Induce Humoral and T cell-mediated in vitro and in vivo Responses in Mugwort Allergy (2003).
J. Allergy Clin. Immunol. 111: 1328-36.

Himly M., Jahn-Schmid B., Pittertschatscher K., Bohle B., Grubmayr K., Ebner H., Ferreira F., and Ebner C.
IgE-mediated Immediate-type Hypersensitivity to the Analgesic Drug Propyphenazone (2003)
J. Allergy Clin. Immunol. 111: 882-8.

Himly M., Jahn-Schmid B., Dedic A., Kelemen P., Wopfner N., Altmann F., van Ree R., Briza P., Richter K., Ebner C., and Ferreira F.
Art v 1, the Major Allergen of Mugwort Pollen is a Modular Glycoprotein with a Defensin-like and a Hydroxyproline-rich Domain (2003).
FASEB J. 17(1):106-8.


Jahn-Schmid B., Kelemen P., Himly M., Bohle B., Fischer G., Ferreira F., and Ebner C.
The T Cell Response to Art v 1, the Major Mugwort Pollen Allergen, is Dominated by One Epitope (2002).
J. Immunol. 169: 6005-11.


Ferreira F., Himly M., Hebenstreit D., Dabrowska U., Vollmann U., Kraft D., Obermeyer G., and Richter K.
Isolation and characterization of cDNA clones coding for mugwort (Artemisia vulgaris) pollen allergens (2001).
Intern. Arch. Allergy Immunol. 124: 77-79.

Pertl H., Himly M., Gehwolf R., Kriechbaumer R., Strasser D., Michalke W., Richter K., Ferreira F., and Obermeyer G.
Molecular and Physiological Characterization of a 14-3-3 Protein from Lily Pollen Grains Regulating the Activity of the Plasma Membrane H+ ATPase During Pollen Grain Germination and Tube Growth (2001).
Planta 213: 132-41.


Aoki M., Schetter C., Himly M., Batista O., Chang H.W., and Vogt P.K.
The Catalytic Subunit of Phosphoinositide 3-Kinase: Requirements for Oncogenicity (2000).
J. Biol. Chem. 275(9): 6267-75.


Hubinger G., Gruber P., Vollmann U., Kraft D., Ferreira F., and Himly M.
Molecular Cloning and Nucleotide Sequence Analysis of a cDNA (Accession No. AF143677) encoding the Cystatin Homologue of Mugwort (Artemisia vulgaris) Pollen (1999).
Plant Physiol. 120: 634 (PGR 99-078).


Ferreira F., Richter K., Engel E., Ebner C., Himly M., Kraft D., and Breitenbach M.
Recombinant Major Allergen of Artemisia vulgaris (Mugwort) Pollen (1998).
European Patent A539/98.

Himly M., Pfleiderer M., Holzer G., Fischer U., Hannak E., Falkner F.G., Dorner F.
Defective Vaccinia Virus as a Biologically Safe Tool for the Overproduction of Recombinant Human Secretory Proteins (1998).
Prot. Expr. Purif. 14(3): 317-26.

Himly M., Foster D.N., Bottoli I., Iacovoni J.S., and Vogt P.K.
The DF-1 Chicken Fibroblast Cell Line: Transformation Induced by Diverse Oncogenes and Cell Death Resulting from Infection by Avian Leukosis Viruses (1998).
Virology 248(2): 295-304.
Cover page.