The HENNER GRAEFF FOUNDATION – YOUNG INVESTIGATOR AWARD

Henner Graeff

We are excited that the HENNER GRAEFF FOUNDATION is sponsoring the Winterschool 2023 with three Young Investigator Awards.
Young investigators are awarded in recognition of their innovative approaches to their specific topics with a prize money of 1000.- EUR each.

 

Awardees:

2023

  • Sam Van Beljouw (Delft University of Technology) Craspase is a CRISPR RNA-guided, RNA-activated protease
  • Frederic Buemi (Imperial College London) Detecting hydrolytic enzymes driving colorectal cancer
  • Peter Grin (University of British Colombia) Defeating an antiviral interferon response by SARS-CoV-2 main protease (3CLpro) cleavage

2022 

  • Natasha Aley (University College London) ATG4B mediates beta catenin expression and 3D spheroid formation in pancreatic ductal adenocarcinoma
  • Naiá Porã Santos (University of Salzburg) Functional analysis of phytocystatin 6 from Arabidopsis thaliana revealed amyloid fibril formation
  • Konstantinos Kalogeropoulos (Technical University of Denmark, Kongens Lyngby) Proteomic and proteolytic landscape of acute human skin repair

2021

  • Matthias Koch (KU Leuven) The mechanism securing GSEC-APP interactions and defining Aβ product length
  • Jimin Hwang (University of Otago /NZ) Design, Synthesis and Biological Evaluation of Anti-chlamydial Covalent Inhibitors Targeting the Novel Bacterial Serine Protease CtHtrA
  • Yekaterina Kovalyova (Yale University) An infection-activated redox switch in the lysosomal protease legumain promotes tumor growth

2020

  • Alaa ALHAYEK (Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland) Succinimides as novel pathoblocker agents targeting extracellular bacterial metalloproteases LasB and ColH
  • Fred ARMBRUST (University of Kiel) APP processing in mouse brains shifts towards β-cleavage upon meprin β overexpression in astrocytes
  • Cynthia COLMORGEN (University of Kiel) Cleavage of galectin-3 by meprin α and meprin β in intestinal mucosa
  • Anna HOFMANN (University of Kiel) Capturing dynamic protein-protein interactions of intermembrane protease SPPL3
  • Giulia MAGNO (Technical University of Munich) Evaluation of the tumor biological role of KLK4 in triple-negative breast cancer
  • Kriti PATHAK (University of Kiel) Biochemical characterization of soluble ADAM10 and ADAM17

 

Best Chairing & Best Speaker – AWARD

YearBest ChairingBest Speaker
2023Ulrich ECKHARD
Institute of Molecular Biology of Barcelona (IBMB)
Xavier GOMIS-RÜTH
Institute of Molecular Biology of Barcelona (IBMB)
Jan POTEMPA
Jagiellonian University		Sam VAN BELJOUW
Delft University of Technology
Craspase is a CRISPR RNA-guided, RNA-activated protease
2022Ulrich ECKHARD
Institute of Molecular Biology of Barcelona (IBMB)
Evelyn HUTTERER
University of Salzburg
Walter STÖCKER
Johannes Gutenberg University of Mainz
2021Barbara GRÜNWALD
University Health Network
2020Ulrich AUF DEM KELLER
ETH Zurich
Christopher  OVERALL
University of British Columbia 		Alaa ALHAYEK
Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland
Succinimides as novel pathoblocker agents targeting extracellular bacterial metalloproteases LasB and ColH
2019 Christoph BECKER-PAULY
University of Kiel
Stefan ROSE-JOHN
Christian-Albrechts-Universität zu Kiel		Stefania WUNDERLI
ETH Zurich
Proteolytic tendon degeneration after physical unloading heavily depends on the patho-physiological niche
2018 Lukas MACH
University of Natural Resources and Life Sciences, Vienna		Rielana WICHERT
University of Kiel
Mucus detachment in the small intestine requires shedding of host metalloprotease meprin β, which is abrogated by pathogenic protease RgpB

2017

Guy SALVESEN
Sanford Burnham Prebys Medical Discovery Institute, LA Jolla

Jessica GÖTZFRIED
Helmholtz Institute Munich
Storage and transportation of donor lungs is extended by α1-antitrypsin as an additive to Perfadex

2016Ulrich AUF DEM KELLER
ETH Zurich		Jennifer VANDOOREN
KU Leuven, Rega Institute for Medical Research
Novel insights in matrix metalloproteinase-9 trimerization and its functional implications
2015Ulrich AUF DEM KELLER
ETH Zurich		Pernille SØGAARD
University of Oxford
DDR1 plays a role in spatial regulation of MT1-MMP activity during epithelial tubulogenesis
2014Jim HUNTINGTON
University of Cambridge		Elfriede DALL
University of Salzburg
Structural and mechanistic basis of legumain inhibition by cystatins
2013Walter STÖCKER
University of Mainz		Claudia BRODER
University of Kiel
It’s Make or Break: The Metalloproteases Meprin α and Meprin β are C- and N-Procollagenases associated with Ehlers-Danlos syndrome VII