The HENNER GRAEFF FOUNDATION – YOUNG INVESTIGATOR AWARD

 

The HENNER GRAEFF FOUNDATION is the sponsor of a new award at the Winterschool 2020, the ‘Young Investigator Award’.

Young investigators are awarded in recognition of their innovative approaches to their specific topics with a total prize money of 1000.- EUR.

 

2021	Matthias Koch KU Leuven	The mechanism securing GSEC-APP interactions and defining Aβ product length
	Jimin Hwang University of Otago /NZ	Design, Synthesis and Biological Evaluation of Anti-chlamydial Covalent Inhibitors Targeting the Novel Bacterial Serine Protease CtHtrA
	Yekaterina Kovalyova Yale University	An infection-activated redox switch in the lysosomal protease legumain promotes tumor growth
2020	Alaa ALHAYEK Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland	Succinimides as novel pathoblocker agents targeting extracellular bacterial metalloproteases LasB and ColH
	Fred ARMBRUST University of Kiel	APP processing in mouse brains shifts towards β-cleavage upon meprin β overexpression in astrocytes
	Cynthia COLMORGEN University of Kiel	Cleavage of galectin-3 by meprin α and meprin β in intestinal mucosa
	Anna HOFMANN University of Kiel	Capturing dynamic protein-protein interactions of intermembrane protease SPPL3
	Giulia MAGNO Technical University of Munich	Evaluation of the tumor biological role of KLK4 in triple-negative breast cancer
	Kriti PATHAK University of Kiel	Biochemical characterization of soluble ADAM10 and ADAM17

Best Chairing & Best Speaker – AWARD

Year	Best Chairing	Best Speaker
2021	Barbara GRÜNWALD University Health Network
2020	Ulrich AUF DEM KELLER ETH Zurich Christopher  OVERALL University of British Columbia	Alaa ALHAYEK Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland Succinimides as novel pathoblocker agents targeting extracellular bacterial metalloproteases LasB and ColH
2019	Christoph BECKER-PAULY University of Kiel Stefan ROSE-JOHN Christian-Albrechts-Universität zu Kiel	Stefania WUNDERLI ETH Zurich Proteolytic tendon degeneration after physical unloading heavily depends on the patho-physiological niche
2018	Lukas MACH University of Natural Resources and Life Sciences, Vienna	Rielana WICHERT University of Kiel Mucus detachment in the small intestine requires shedding of host metalloprotease meprin β, which is abrogated by pathogenic protease RgpB
2017	Guy SALVESEN Sanford Burnham Prebys Medical Discovery Institute, LA Jolla	Jessica GÖTZFRIED Helmholtz Institute Munich Storage and transportation of donor lungs is extended by α1-antitrypsin as an additive to Perfadex
2016	Ulrich AUF DEM KELLER ETH Zurich	Jennifer VANDOOREN KU Leuven, Rega Institute for Medical Research Novel insights in matrix metalloproteinase-9 trimerization and its functional implications
2015	Ulrich AUF DEM KELLER ETH Zurich	Pernille SØGAARD University of Oxford DDR1 plays a role in spatial regulation of MT1-MMP activity during epithelial tubulogenesis
2014	Jim HUNTINGTON University of Cambridge	Elfriede DALL University of Salzburg Structural and mechanistic basis of legumain inhibition by cystatins
2013	Walter STÖCKER University of Mainz	Claudia BRODER University of Kiel It’s Make or Break: The Metalloproteases Meprin α and Meprin β are C- and N-Procollagenases associated with Ehlers-Danlos syndrome VII