Theses


Doctoral theses performed in the Lab of Fatima Ferreira Sabrina Wildner: Structural features of biologics: Characterization of allergen molecules and biopharmaceuticals, (2013 – 2018), University of Salzburg Lorenz Aglas: Intrinsic properties of the Bet v 1 fold: impact on immunogenicity and allergenicity, (2013 – 2017), University of Salzburg Martin Wolf: Amb a 1 isoforms: the non-equal siblings, (2012 – 2017), University of Salzburg Isabel Maria Pablos O’Campo: Physicochemical and immunological characterization of the relevant inhalant allergens in Europe and India, (2012 – 2017), University of Salzburg Teresa Stemeseder: Molecular IgE profiling and evaluation of disease-influencing factors in allergy, (2013 – 2016), University of Salzburg Stephanie Eichhorn: Novel molecular diagnostics and therapeutics for food and weed pollen allergy (2013 – 2016), University of Salzburg Heidi Hofer: Destroying IgE-binding while preserving immunogenicity: the new roadmap to develop safe and efficacious allergy vaccines (2012 – 2016), University of Salzburg Markus Steiner: Characterization of the non-anaphylactic activation of diclofenac on whole blood-derived human basophils (2011 – 2015), University of Salzburg Anargyros Roulias: Structural manipulations of Bet v 1 homologues and the impact on their immune properties. PhD-Thesis (2008-2014), University of Salzburg Eva Vejvar: Identification and molecular characterization of novel plant food and pollen allergens and their impact on IgE cross-reactivity. PhD-Thesis (2010-2013), University of Salzburg Claudia Asam: Uncovering allergy-eliciting intrinsic properties of pollen allergens. PhD-Thesis (2010- 2013), University of Salzburg Ulrike Pichler: Development of novel tools for allergy diagnosis and therapy. PhD-Thesis (2010-2013), University of Salzburg Andrea Harrer: Mechanistic investigation of systemic hypersensitivity caused by the nonsteroidal anti-inflammatory drug diclofenac. PhD-Thesis (2006-2009), University of Salzburg Michael Hauser: Creation of a pollen hybrid for immunotherapy of birch and associated pollen allergies. PhD-Thesis (2006-2009), University of Salzburg Matthias Egger: A study on processing of the Artemisia vulgaris pollen major allergen Art v 1 by human antigen presenting cells. PhD-Thesis (2004-2008), University of Salzburg Sonja Mutschlechner: Characterization of naturally processed and presented peptides of Bet v 1, the major allergen from birch pollen. PhD-Thesis (2004-2008), University of Salzburg Gabriele Gadermaier: Hypoallergenic variants of Art v 1, the major mugwort pollen allergen: possible candidate molecules for treatment of type I allergy. PhD-Thesis (2001-2005), University of Salzburg Gudrun Hubinger: Amb a 1 and its homologous 40.9 kDa allergen in mugwort pollen. PhD-Thesis (2002-2005), University of Salzburg Michael Wallner: Expression and characterization of Bet v 1 variants created by gene shuffling. PhD-Thesis (2002-2004), University of Salzburg Petra Gruber: Production of recombinant single-chain Fv antibody fragments specific for the hydroxyproline-rich domain of natural Art v 1 by phage-display. PhD-Thesis (2002-2004), University of Salzburg Azra Dedic: Isoforms of Art v 1, the major mugwort pollen allergen. PhD-Thesis (2001-2004), University of Salzburg Nicole Wopfner: Cross-reactive allergens in pollen from weeds. PhD-Thesis (1999-2003), University of Salzburg Martin Himly: Biochemical and immunological investigations of atopic and nonatopic allergens. PhD-Thesis (1997-2001), University of Salzburg

Diploma/Master theses performed in the Lab of Fatima Ferreira Tamara Weidinger: Production and in depth characterization of major inhalant allergens and derivatives thereof (2016-2017), University of Salzburg Maria Alejandra Parigiani: Novel strategies in allergy vaccine design. Diploma-Thesis (2014-2015), University of Salzburg Bianca Kastner: Cloning of Humulus japonicus pollen allergens and purification and characterization of the Periplaneta americana allergen Per a 1. Diploma-Thesis(2014-2015), University of Salzburg Bettina Schweidler: Purification and characterization of the Periplaneta americana allergen Per a 3 and analysis of exposure and sensitization to indoor allergens in different Austrian regions. Diploma-Thesis(2014-2015), University of Salzburg Christine Kapfhammer: Relevance and IgE cross-reactivity of mugwort pollen allergen for chestnut sensitized patients. Diploma-Thesis (2012-2013), University of Salzburg Lorenz Aglas: Recombinant production and protein purification of the major allergen of Cupressus arizonica (cypress) Cup a 1 and development of a hypoallergenic variant of Cup a 1. Diploma-Thesis (2012-2013), University of Salzburg Milijana Roljic: Development and optimization of a surface modification technique for polymeric DNA and protein microarrays and production of a defensin-like protein from ragweed pollen. Diploma-Thesis (2012-2013), University of Salzburg Astrid Haab: Generation and Characterization of Bet v 1 Variant Proteins. Diploma-Thesis (2012-2013), University of Salzburg Heidi Hofer: Generation of safe and efficacious allergy vaccines. Diploma-Thesis (2011-2012), University of Salzburg Angelika Hörschläger: Development of a hypoallergenic Pru p 3 variant and investigation of chestnut as cross-reactive allergen source. Diploma-Thesis (2011-2012), University of Salzburg Stephanie Eichhorn: Generation of new candidate molecules for treatment of LTP-related food allergy and Plantago lanceolata: an important sensitizer for summer pollinosis. Diploma-Thesis (2011-2012), University of Salzburg Andreas Koller: Development and validation of polymer biochips for DNA and protein microarray applications. Diploma-Thesis (2011-2012), University of Salzburg Barbara Hainz: Identifizierung neuer Allergene im Pollen von Plantago lanceolata (Spitzwegerich) und Corylus avellana (Hasel). Diploma-Thesis (2011-2012), University of Salzburg Roland Lasshofer: Recombinant production and immunological characterization of Artemisia vulgaris and Ambrosia artemisiifolia pollen allergens by ELISA. Diploma-Thesis (2010-2011), University of Salzburg Alexander Jürets: In vitro endo-/lysosomal proteolysis and antigen uptake of recombinant allergens. Diploma-Thesis (2010-2011), University of Salzburg Martin Wolf: Purification and detailed characterization of natural pectate lyases causing type I hypersensivitey. Diploma-Thesis (2009-2010), University of Salzburg Leif Krückemeier: Immunological and physicochemical characterization of recombinant panallergens. Diploma-Thesis (2009-2010), University of Salzburg Markus Steiner: Establishment of a basophil activation test for NSAID hypersensitivity. Diploma-Thesis (2009-2010), University of Salzburg Eva Vejvar: Identification and characterization of allergens involved in pollinosis-related food allergies. Diploma-Thesis (2009-2010), University of Salzburg Werner Auzinger: Production and immunological characterization of murine monoclonal antibodies against the mugwort pollen allergen Art v 3. Diploma-Thesis, (2009-2010), University of Salzburg Jennifer Moser: Plant-based expression of Art v 1, the major mugwort pollen allergen. Diploma-Thesis (2008-2009), University of Salzburg Claudia Asam: The effect of ligand-binding on immunogenicity and allergenicity of Bet v 1 isoforms, Diploma-Thesis (2008-2009), University of Salzburg Julia Wenger: Establishment of alternative expression systems for the expression of Amb a 1 – the major ragweed pollen allergen. Diploma-Thesis (2008-2009), University of Salzburg Florian Reisinger: Production of monoclonal antibodies against the major mountain cedar allergen Jun a 1, Diploma-Thesis (2008-2009), University of Salzburg Monica Gimpl: Development of antibody-based assays for detection of dicolfenac (DF) and DF-haptenized components in human blood, Diploma-Thesis (2007-2008), University of Salzburg Tamara Girbl: Identification and characterization of a novel lipid transfer protein from celery, Diploma-Thesis (2007-2008), University of Salzburg Stephanie Wallner: Amb a 1, the major ragweed allergen: cloning and immunological characterization of Amb a 1 cleavage mutants, Diploma-Thesis (2007-2008), University of Salzburg Eva Klinglmayr: Bet v 1, the major birch pollen allergen and homologous allergens in trees and foods: approaches for safer specific immunotherapie, Diploma-Thesis (2005-2006), University of Salzburg Gabriele Schmutzler:The family of non-specific lipid transfer proteins in weed pollen. Diploma-Thesis (2005-2006), University of Salzburg Franz Zimmermann: IgE epitope engineering of Bet v 1 and Mal d 1 allergens. Diploma-Thesis (2004-2006), University of Salzburg Ulrich Koller: Creation of hypoallergens by setting specific mutations in the amino acid sequence of the shuffled allergens H2 and H3. Diploma-Thesis (2004-2005), University of Salzburg Reinhard Schwarz: Celery-mugwort-spice syndrome: a possible involvement of non-specific Lipid transfer proteins. Diploma-Thesis (2003-2004), University of Salzburg Sonja Mutschlechner: Production of biotinylated fusion allergens for a lectin-mediated antigen delivery to antigen-presenting cells. Diploma-Thesis (2002-2004), University of Salzburg Matthias Egger: Art v 1, the major mugwort allergen: recombinant production approaches and the characterization of cross-reactivity with other allergens. Diploma-Thesis (2002-2004), University of Salzburg Michael Wallner: In vitro evolution of the Bet v 1 family by gene shuffling. Diploma-Thesis (2001-2002), University of Salzburg Gudrun Hubinger: Cross-reactive allergens in ragweed and mugwort pollen. Diploma-Thesis (2000-2002), University of Salzburg Petra Gruber: Recombinant production, purification and characterization of calcium-binding allergens. Diploma-Thesis (2000-2002), University of Salzburg Azra Dedic: Purification and immunochemical characterization of Art v 1, the major pollen allergen of Artemisia vulgaris .Diploma-Thesis (1999-2001), University of Salzburg Marta Dabrowska: Isolation and characterization of allergens from Artemisia vulgaris pollen. Diploma-Thesis (1999-2001), University of Salzburg Gabriele Gadermaier: Generation and characterization of cysteine-variants of Art v 1, the major mugwort pollen allergen. Diploma-Thesis (1999-2001), University of Salzburg Daniel Hebenstreit: Calcium-binding allergens from pollen. Diploma-Thesis (1998-2000), University of Salzburg