Selected Publications

  • Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER. Heusermann W, Hean J, Trojer D, Steib E, vonBueren S, Graff-Meyer A, Genoud C, Martin K, Pizzato N, Voshol J, Morrissey D, ElAndaloussi S, Wood MJ, Meisner-Kober N.  Journal of Cell Biology 2016, Apr 25;213(2):173-84.
  • Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties. Nordin JZ, Lee Y, Vader P, Mäger I, Johansson HJ, Heusermann W, Wiklander OP, Hällbrink M, Seow Y, Bultema JJ, Gilthorpe J, Davies T, Fairchild PJ, Gabrielsson S, Meisner-Kober NC, Lehtiö J, Smith CI, Wood MJ, El Andaloussi S. Nanomedicine. 2015 May;11(4):879-83.
  • Highly complementary target RNAs promote release of guide RNAs from human Argonaute2. De N, Young L, Lau PW, Meisner-Kober N, Morrissey D, MacRae I. Mol Cell (2013), May 9;50(3):344-55.
  • The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing. Stalder L, HeusermannW, Sokol L, Trojer D, Wirz J, Hean J, Fritzsche A, Aeschimann F, Pfanzagl V, Basselet P, Weiler J, Hintersteiner M, Morrissey DV, Meisner-Kober NC. EMBO J (2013); Apr 17;32(8):1115-27.
  • Terminal Adenosyl Transferase activity of posttranscriptional regulator HuR revealed by confocal on-bead screening. Meisner NC, Hintersteiner M, Seifert JM, Bauer R, Benoit RM, Widmer A, Schindler T, Uhl V, Lang M, Gstach H, Auer M. (2009)Journal of Molecular Biology, 2009, 3(8), p.435-50.
  • Identification and mechanistic characterization of low molecular weight inhibitors for HuR. Meisner NC, Hintersteiner M, Mueller K, Bauer R, Seifert JS, Naegeli HU, Ottl J, Oberer L, Guenat C, Moss S, Harrer N, Woisetschlager M, Buehler C, Uhl V, Auer M. Nature Chemical Biology, 2007, Aug;3(8):508-15.